Systems Biology (M-I-T)

• Introduction to the Systems Biology
• Input function, Michaelis-Menten kinetics, and cooperativity
• Autoregulation, feedback and bistability
• Synthetic biology and stability analysis in the toggle switch
• Oscillatory genetic networks
• Graph properties of transcription networks
• Feed-forward loop network motif
• Introduction to stochastic gene expression
• Causes and Consequences of Stochastic Gene Expression
• Stochastic Modeling
• Life at Low Reynold’s Number
• Robustness and Bacterial Chemotaxis
• Robustness in Development and Pattern Formation
• Microbial Evolution Experiments and Optimal Gene Circuit Design
• Evolution in Finite Populations
• Clonal Interference and the Distribution of Beneficial Mutations
• Fitness Landscapes and Sequence Spaces
• Evolutionary Games
• Survival in Fluctuating Environments
• Parasites, the Evolution of Virulence and Sex
• Interspecies Interactions
• Ecosystem Stability, Critical Transitions, and Biodiversity
• The Neutral Theory of Ecology